Preprocessing data

Preprocessing data for methylation by selecting data from two given samples if methylation probe exists in both samples on the same chromosome and position.

preprocessing(sample.1, sample.2)

Arguments

sample.1	a data frame with methylation data
sample.2	a data frame with methylation data

Value

data.frame with methylation values on common positions and chromosomes from sample.1 and sample.2

Examples

# data from package
data('schizophrenia')
control <- schizophrenia %>% filter(category == 'control') %>%
dplyr::select(-category)

disease <- schizophrenia %>% filter(category == 'disease') %>%
 dplyr::select(-category)

data <- preprocessing(control, disease)
head(data)
#>    chr   poz prob no meth unmeth meth.rate
#> 1 chr1 81412    x 35   29      6 0.8285714
#> 2 chr1 81412    y 76   66     10 0.8684211
#> 3 chr1 81442    x 35   29      6 0.8285714
#> 4 chr1 81442    y 76   66     10 0.8684211
#> 5 chr1 81546    x 35   29      6 0.8285714
#> 6 chr1 81546    y 76   66     10 0.8684211